• Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines 

      von Hofsten, Susannah; Langer, Manuel K; Korelin, Katja; Norvoll Magnussen, Synnøve; Ausbacher, Dominik; Anderssen, Trude; Salo, Tuula; Strøm, Morten B.; Bayer, Annette; Al-Samadi, Ahmed; Berge, gerd (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-30)
      The incidence of head and neck squamous cell carcinoma (HNSCC) is increasing and the conventional treatments for this form of cancer can be tough. Despite the success of existing immunotherapies in some HNSCC patients, many do not respond to this type of treatment. Thus, the development of novel anti-cancer therapies should be prioritized. In the current study, the anticancer activity of a panel ...
    • The effect of interleukin-17F on vasculogenic mimicry in oral tongue squamous cell carcinoma 

      Almahmoudi, Rabeia; Salem, Abdelhakim; Hadler-Olsen, Elin Synnøve; Svineng, Gunbjørg; Salo, Tuula; Al-Samadi, Ahmed (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-20)
      Oral tongue squamous cell carcinoma (OTSCC) is one of the most common cancers worldwide and is characterized by early metastasis and poor prognosis. Recently, we reported that extracellular interleukin-17F (IL-17F) correlates with better disease-specific survival in OTSCC patients and has promising anticancer effects in vitro. Vasculogenic mimicry (VM) is the formation of an alternative vasculogenic ...